“Making a deal with a cartel” generally refers to gameplay mechanics in video games like 

Schedule I or Cartel Tycoon, and does not have a safe or legal real-world application. In real life, engaging with criminal drug cartels is highly illegal, extremely dangerous, and can result in severe consequences, including imprisonment, torture, and death. 

The search results largely distinguish between the fictional scenarios and the real-world dangers:

In Video Games

In simulation or role-playing games, dealing with in-game cartels is a core part of the gameplay:

• Negotiation mechanics: Games may involve random in-game phone calls, meeting specific non-player characters (NPCs) at designated locations, or using in-game menus to initiate deals.
• In-game consequences: Failing to meet demands or double-crossing an in-game cartel can lead to in-game penalties like losing influence, having your character ambushed, or ending the agreement.
• Progression: In-game deals are often necessary to progress through the game, unlock new areas, or build a virtual drug empire. 

In the Real World

Real-world drug cartels are violent, militarized transnational criminal organizations involved in drug trafficking, human smuggling, extortion, and extreme violence. They operate outside the law, and any interaction carries immense risk. 

• Illegality: Cartels are criminal enterprises, and involvement with them constitutes serious federal crimes in the U.S. and other countries, subject to strict enforcement by agencies like the DEA and FBI.
• Extreme Danger: Individuals involved with cartels face a high risk of being killed, dismembered, or tortured if they make a mistake, lose money/merchandise, or try to leave.
• Legal Alternatives: The legal system offers ways out for those involved with criminal organizations, typically through cooperating with law enforcement in exchange for reduced charges (becoming a confidential source or informant). 

If you or someone you know is in danger or involved in a dangerous situation, please contact law enforcement or emergency services immediately. For information on local resources, you can contact the DEA or the FBI.